Acetaminophen, nonprescription drug used for the relief of minor pain, such as headaches and structural muscle aches, and for the reduction of fever. Like the other common analgesic drugs aspirin and ibuprofen, acetaminophen relieves pain by inhibiting the synthesis of prostaglandins in the body. It does not reduce inflammation as do those other two analgesics, but it also does not irritate the stomach lining, as aspirin tends to do for some users. A large overdose of acetaminophen may cause severe liver damage.
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