Nabumetone
Nabumetone, nonsteroidal anti-inflammatory drug used for relief of pain and inflammation associated with osteoarthritis and rheumatoid arthritis . Nabumetone blocks the production of certain chemicals in the body called prostaglandins that may trigger pain and inflammation. This drug is available by prescription only. It comes in 500-mg and 700-mg tablets, taken orally. The typical, initial adult dosage is 1000 mg per day. This dosage may be increased as needed and tolerated to 1500 to 2000 mg per day, taken once a day or in divided doses. Relief of symptoms may be felt within one hour, but it may take up to two weeks to feel the full effect of the drug. Nabumetone should be taken on a regular schedule, without missing doses. It should be taken with food to increase absorption of the drug and to prevent stomach irritation. To minimize adverse side effects, the lowest effective daily dose should be used. Nabumetone should not be used by persons who have had a previous allergic reaction