Spasm
Spasm, involuntary and abnormal violent contraction of muscles or muscle tissue. Tonic spasm, or cramp, is characterized by an unusually prolonged and strong muscular contraction, with relaxation taking place slowly. The extreme example of tonic spasm is tetanus , in which the spasms are so violent and so enduring that they may paralyze breathing. In the other form of spasm, called clonic spasm, contractions of the affected muscles take place repeatedly, forcibly, and in quick succession, with equally sudden and frequent relaxations. The most typical examples of clonic spasm are epilepsy and convulsive hysteria. The medicines used to counteract spasmodic muscular activity are termed antispasmodics. These are used in certain surgical procedures because they block transmission of nervous impulses to the muscles. Derivatives of hemlock and some 50 other plants have a relaxing effect on muscles.