Etodolac

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Etodolac, drug used to treat osteoarthritis. Etodolac is a nonsteroid, mild analgesic that works by reducing concentrations of certain chemicals in bodily tissues that produce inflammation and pain, relieving swelling and stiffness.

Etodolac is available only by prescription. Capsules or tablets of etodolac are taken orally every six to eight hours, usually in 200 to 400 mg doses. The total daily dosage should not exceed 1200 mg. Capsules should be taken with food and a full glass of water. (Not lying down for 20 to 30 minutes after taking the drug can help avoid stomach upset.) Effectiveness of this drug may not been seen for one to two weeks after beginning treatment.

Patients who experience allergic reactions to aspirin or related medications should not take etodolac. Patients with kidney or liver problems, peptic ulcer, heart disease, or high blood pressure should use this drug with caution. Its safety for use during pregnancy is not known, and it may appear in breast milk. Children under age 12 should not use this drug.

Ulcers or internal bleeding are sometimes caused by this medication. Other possible side effects include abdominal pain, indigestion, nausea, constipation, diarrhea, fever, dizziness, ringing in the ears, or muscle weakness. Occasionally seen are fluid retention, sweating, anemia, fainting, insomnia, rapid heartbeat, skin rash, or yellowing of the skin or eyes.

This drug may interact adversely with aspirin, blood-thinning medications, diuretics, and digoxin.

Brand Name: Lodine

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