Rabies

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Rabies, acute, contagious infection of the central nervous system, caused by a specific virus that enters the body through the bite of an animal. All warm-blooded animals are susceptible, but in North America the disease is most common in skunks, foxes, bats, raccoons, dogs, and cats. Most of the cases of rabies in humans are caused by the bite of one of these animals. The incubation period in humans varies from three weeks to 120 days, with an average of about four to six weeks. Rabies is virtually always fatal when vaccine is not administered.

Modern treatment, following a bite by a rabid or presumed rabid animal, consists of immediate and thorough cleansing of the bite wound and injection into the wound and elsewhere of hyperimmune antirabies serum. A 14- to 30-day course of daily injections of rabies vaccine is then given; booster doses are given 10 days after this course and again 20 days later.

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