Hodgkin’s Disease

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Hodgkin’s Disease or Hodgkin's Lymphoma, less severe form of two types of cancer that arise in the lymphatic system (network of small vessels that carry lymph, a fluid containing white blood cells of the immune system). The other form is non-Hodgkin's lymphoma. Hodgkin's disease is characterized by usually painless but progressive enlargement of lymph nodes (or glands) and other lymphoid tissue.

Diagnosis of Hodgkin's disease is made with a biopsy (removal of a small tissue sample for examination under a microscope). Hodgkin's disease is primarily distinguished from non-Hodgkin's lymphoma by the presence of Reed-Sternberg cells, large cells that contain several nuclei. If the disease is diagnosed at an early stage and has not metastasized (spread to other areas of the body), radiation therapy is commonly used. With advanced cases, the doctor will usually prescribe chemotherapy (anti-cancer drugs) for approximately six months, often in combination with radiation therapy. For patients with disease resistant to conventional treatments, or for patients who have relapses (reappearance of symptoms after an apparent cure), doctors may try high-dose chemotherapy and bone-marrow transplants. The chemotherapy destroys all of the patient's unhealthy bone marrow in preparation for the transplantation of healthy bone marrow, so the body can once again produce healthy white blood cells. The healthy bone marrow is injected into the bloodstream and, if successful, the cells find their way to the bones and begin to grow

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