Ketoprofen

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Ketoprofen, drug used to reduce the inflammation, fever, and pain associated with such diseases as arthritis, bursitis, tendinitis, and menstrual cramps. Ketoprofen is believed to work by preventing prostaglandins (chemicals that cause inflammation and contribute to the brain’s perception of pain) from concentrating in body tissues.

Ketoprofen is available by prescription in capsule, tablet, and suppository form. The drug is taken daily in 3 or 4 doses for a total of 150 to 300 mg. It is most effectively absorbed if taken on an empty stomach, but it can be taken with food, milk, or an antacid to prevent stomach irritation. The patient must take ketoprofen for one to three weeks before physicians can evaluate its effectiveness.

Possible side effects include drowsiness, fluid retention, skin rash, headache, depression, indigestion, and nausea. Men may experience problems with sexual performance and breast enlargement. Women may find their menstrual cycles affected, with increased blood flow during menstruation.

Pregnant women should not use ketoprofen in the third trimester of pregnancy. Breast-feeding women, patients with allergies to the drug, those who suffer asthma with aspirin use, and patients with ulcers, bleeding disorders, impaired kidney function, or liver disease should not take ketoprofen.

Ketoprofen may have negative effects when taken with other anti-inflammatory drugs, steroids, aspirin, insulin, phenytoin, verapamil, nifedipine, lithium, and diuretics. Alcoholic beverages can increase the risk of ulcers or bleeding in the stomach.

Brand Name: Orudis

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